We’ve adopted a novel approach to affinity maturation. Experience helps us deliver an antibody optimization service that increases the binding and considers manufacturing, stability, or immunogenicity.
Using our Rational Affinity Maturation Platform (RAMP®), we can help those who want to develop the best possible antibody sequence by exploring their antibody’s natural somatic hypermutation space and introducing diversity both in the frameworks and the CDRs.
We don’t use phage display in our approach. We do something different.
Read our short case study about the results we have delivered with Cathepsin S, using our unique affinity maturation platform RAMP®
We use a totally novel approach to generating diversity, therefore exploring new sequence space that other approaches will not do. Diversity is key! Our studies and experience teach that the framework regions, not only impact stability, but also binding. Our approach allows new sequences to be found that have unpredictable and beneficial consequences.
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mint_design2020-07-21 09:34:202022-04-05 10:46:31Therapeutic antibodies: the scale of the manufacturing challenge
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mint_design2019-11-29 12:15:332022-04-05 10:47:06Making your best antibody better
info@fusionantibodies.com
+44 (0)28 9043 2800
Investor and Media
+44 (0)20 7933 8780
fusion@walbrookpr.com
Fusion Antibodies PLC, Springbank Industrial Estate, 1 Springbank Rd, Dunmurry, Belfast BT17 0QL