Ideal drug or dead-end molecule?

Are you ready to move to transient protein expression? On the surface, an antibody molecule can look like an ideal candidate but what if you looked a little closer?

In-depth characterization is a vital stage in scaling up your molecule for transient protein expression and ultimately stable cell line development.

Spending time on a transient protein expression pilot program can help you rule out dead-end molecules and avoid nasty surprises at a later stage.

5 top tips for a transient protein expression pilot

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Think you know your molecule?

Having the ability to distinguish an ideal drug candidate from a dead-end molecule at this stage is an absolute must for a successful drug developer.

In this example, the presence of multimers and aggregates, only identified by a more thorough analysis, skew the affinity results and mask a low quality preparation of antibody.

Deep analysis of function, purity and protein quality is therefore vital.

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About Fusion Antibodies

We are world leaders in antibody development services specializing in the discovery, engineering and supply of pre-clinical biologics to clinical Cell Line Development.

Fusion offers flexibility and agility while delivering clinical candidates focusing on developability, manufacturability and function.

Get in touch to discuss your requirements